Noun

1. The act of losing or surrendering something as a penalty for a mistake or fault or failure to perform etc.
2. Personnel that are sacrificed (e.g., surrendered or lost in order to gain an objective)
3. A loss entailed by giving up or selling something at less than its value
4. The act of killing (an animal or person) in order to propitiate a deity
5. (baseball) an out that advances the base runners

Verb

1. Endure the loss of
2. Kill or destroy
3. Sell at a loss
4. Make a sacrifice of; in religious rituals